can valtrex cause false negative

Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. My ex also found out that her score for her test taken in Feb was a 1.4 and that her previous two partners were negative. I did have around like 10 separate lesions during my first outbreak. An iGg test can detect 95% of hsv-2 and 70% of hsv-1 infections. So should I assume that the IGM test was a false positive for HSV-2 being that i have had chicken pox before and the fact I am HSV-1 positive for the antibodies both which can cause cross re activity for the IgM test. In your body, valacyclovir becomes the anti-herpes medicine, acyclovir. People with symptoms can have one or more blisters on or around the genitals, rectum, or mouth. The average household teaspoon may not hold the right amount of liquid. 2 Lower thresholds may be used in clinical settings, as the cutoff values defined by the DHHS Sorry! An iGg test can detect 95% of hsv-2 and 70% of hsv-1 infections. I've only recently had days w little no zero symptoms, such as all the sensations you described. Although current treatment recommendations from the Centers for Disease Control and Prevention (CDC) are considered adequate,22 careful follow-up with serial serologic tests, clinical assessment and CSF examination (in the case of neurosyphilis) is necessary. Valtrex and Drug screen false positive - a phase IV clinical study of FDA data Summary: Drug screen false positive is found among people who take Valtrex, especially for people who are female, 30-39 old. Yes. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Taking Valtrex (valacyclovir) does not change the test results for the usual STD tests, including HIV tests. 2016;41(8):26-30.. ABSTRACT: Urine drug screening is a common way to test for compliance with medications having high abuse potential. The diagnosis and treatment of syphilis can present difficult dilemmas. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Thank you for responding! changes in behavior, especially in interactions with other people, changes in patterns and rhythms of speech, fast, pounding, or irregular heartbeat or pulse, feeling that others are watching you or controlling your behavior, feeling that others can hear your thoughts, feeling, seeing, or hearing things that are not there, lightheadedness when getting up from a lying or sitting position, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, seeing, hearing, or feeling things that are not there, shakiness in the legs, arms, hands, or feet, sores, ulcers, or white spots on the lips or in the mouth, swelling of the face, fingers, or lower legs, talking, feeling, and acting with excitement, trembling or shaking of the hands or feet, unsteadiness, trembling, or other problems with muscle control or coordination, Blistering, peeling, or loosening of the skin, increased sensitivity of skin to sunlight, redness or other discoloration of the skin. Most people who have HSV-1 or HSV-2 don't have symptoms. Other dilemmas may be encountered in the treatment of patients who have concurrent human immunodeficiency virus infection. Valacyclovir is used to treat herpes virus infections, including herpes labialis (also known as cold sores), herpes zoster (also known as shingles), and herpes simplex (also known as genital herpes) in adults. Valtrex negative false best place. Malaise, fever, sore throat, headache, arthralgia, generalized lymphadenopathy, Syphilitic meningitis with cranial nerve palsies; iritis with anterior uveitis, Asymptomatic; detectable by abnormal serologic test results, Cardiovascular syphilis: aortic aneurysm, aortic regurgitation, nonatherosclerotic coronary artery disease, Tabes dorsalis: lightning pains, pupillary abnormalities, ataxia, lower extremity reflex abnormalities, incontinence, General paresis: dementia with slurred speech, papillary abnormalities, reflex abnormalities, tremor, seizures, Tertiary syphilis, without neurologic symptoms, Human immunodeficiency virus infection and late latent syphilis or syphilis of unknown duration, Patient preference (in immunocompetent patient), Benzathine penicillin G, 2.4 million U IM one time, In penicillin-allergic patients: doxycycline, 100 mg orally twice daily for 2 weeks, or tetracycline, 500 mg orally 4 times daily for 2 weeks. The Jarisch-Herxheimer reaction, although not more common in pregnancy, can cause premature uterine contractions and fetal distress.24 Because the consequences of congenital syphilis, both early (stillbirth, prematurity, anemia, thrombocytopenia)25 and late (deafness, mental retardation, seizures, bony deformities),26 are severe, these prenatal risks should not alter the decision to treat the patient, but careful observation is necessary. The purpose of treatment in such cases is to arrest further disease progression. I was diagnosed with genital herpes January 2012 by visual exam by doctor and classic symptoms. Connect by text or video with a U.S. board-certified doctor now wait time is less than 1 minute!We are asking our website visitors to consent to the use of cookies by . If you start taking any of the standard herpes medications (ie valtrex, acyclovir or famciclovir) before your body has generated enough antibodies to be detected on an IgG test then these medications will slow antibody production and extend the time needed before an IgG test will be accurate. The more common side effects of valacyclovir can include: headache. I also have a friend who has had heroes for 9yrs and she's come up negative every time and suspected valtrex was the culprit, so she stopped it for awhile and was actually waiting for an ob and it didn't happen, but that time her blood test did come back positive. second opinion please. If you test positive, but your risk for getting the virus is low, you may need to be tested again. Depends upon the test to which you are referring. Patients who have had syphilis of unknown duration and who have high (greater than 1:32) nontreponemal serologic test titers are considered to be infected with early syphilis. Current CDC recommendations are that patients with late latent syphilis or syphilis of unknown duration should undergo a diagnostic lumbar puncture. I got retested just to make sure I didnt have anything else. Those with genital herpes may be prescribed Valtrex for extended periods of time in an effort to reduce outbreaks. Nervous system problems: agitation, h allucinations, confusion, aggressive behavior, seizures, and speech problems. Valtrex ( valacyclovir) may diminish the presence of virus in the skin or mucous membranes lesions and lessen the chances of a viral culture being positive, but will not in any way alter the antibody test on a blood specimen. Call your doctor for medical advice about side effects. Other parameters, including VDRL results, can remain positive for more than a year after treatment of neurosyphilis. Serious side effects of Valtrex. I develop flu like symptoms but not sure if it was the actual flu or from a herpes infection. Thus, patients with late latent syphilis or syphilis of unknown duration present a common management problem. The areas affected by genital herpes, chickenpox, or shingles should be kept as clean and dry as possible. Can you contract HSV other ways besides sexual contact? Symptoms of syphilitic meningitis and, to a lesser extent, meningovascular syphilis usually resolve with treatment. The igGs were negative. Once the stage of syphilis is determined, choosing an appropriate treatment regimen is usually straightforward (Table 4).6 In patients with primary, secondary or early latent syphilis, the recommended treatment is a single intramuscular injection of benzathine penicillin G, in a dosage of 2.4 million U. All Rights Reserved. Took Valtrex the week leading up to a IGG blood test which I took soon after my first outbreak Can Valtrex cause false negative for IGG? I'm absolutely floored! All of the signs and symptoms of primary or secondary syphilis usually resolve with or without treatment. This is true until the sores are completely healed and the scabs have fallen off. Or you can ask Terri the same questions directly. Another possible cause of a false negative result is an Ectopic pregnancy. For non-prescription products, read the label or package ingredients carefully. This will keep your kidneys working well and help prevent kidney problems. Patients with penicillin allergy can be treated with alternative regimens if they have primary or secondary syphilis. The question of whether to evaluate CSF in patients with latent syphilis is a frequent clinical problem. Cardiovascular manifestations of tertiary syphilis are uncommon. With syphilis at an all-time low in the United Statesoccurring at a rate of 3.2 cases per 100,000 population1the future holds lationthe future holds hope for eradication of this disease. Wondering what someone else might think. My doctor recommended the same thing. Is there any chance herpes 1 can come back negative? Tk you! In general, current HIV tests are highly accurate. (IgG) came back with a normal result of 0.17. The most common dilemmas posed by diagnosis and treatment of syphilis are how to interpret serologic studies, when to perform a lumbar puncture and how to assess the patient's response to therapy. Valacyclovir is used to treat herpes virus infections, including herpes labialis (also known as cold sores), herpes zoster (also known as shingles), and herpes simplex (also known as genital herpes) in adults. Herpes simplex virus type 1 (HSV-1) or herpes simplex virus type 2 (HSV-2) cause genital herpes. Does Valtrex suppress virus enough to show negative in a blood test? Didn't find the answer you were looking for? Please see our Wiki page on herpes testing for more information about this. In patients with neurosyphilis, repeat lumbar punctures should be performed at six-month intervals until the CSF pleocytosis resolves. Although it's rare, Valtrex can cause more serious side effects that may require medical help, including: Kidney failure. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. readmore. That insect crawling I the worst feeling. Herpes infection of the genitals can be caught from or spread to your partner during any sexual activity. Still looking for answers? Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Started Valtrex immediately and been on it a year, then decided to take another test January 2013 which also showed negative. We offer this Site AS IS and without any warranties. There are reports of HIVinfected patients who have persistent or recurrent syphilis despite appropriate antisyphilitic therapy.21,23 In addition, the serologic response to therapy is often less predictable in HIVpositive patients than in HIVnegative patients, particularly those with primary or secondary syphilis. This constellation of symptoms is described by the mnemonic PARESIS: personality disturbances, affect abnormalities, reflex hyperactivity, eye abnormality, sensorium changes, intellectual impairment and slurred speech.2 The ocular abnormality is manifested as Argyll-Robertson pupils (small, irregular pupils bilaterally, nonreactive to light but reactive to accommodation). ChildrenUse and dose must be determined by your doctor. This was after 2 1/2 weeks of valtrex. Never disregard or delay professional medical advice in person because of anything on HealthTap. Have a follow up test soon but I'm pretty positive it's herpes :(. This distinction is important because therapies for early latent and late latent syphilis are different. Read our editorial policy. Both the lesion and rash resolve without treatment. Doctors typically provide answers within 24 hours. Something else that can cause a false positive is a molar pregnancy. I was just diagnosed with HSV along with bacterial vaginosis. Along with its needed effects, a medicine may cause some unwanted effects. This is known as having an "outbreak." Conversely, in late syphilis, about one fourth of untreated patients have negative VDRL results.8 Therefore, the nontreponemal tests cannot be relied on for diagnosis when the disease is in its very early or late stage. HSV-2 IgG antibodies .16 <.90. Initial screening for syphilis is performed with one of the nontreponemal antibody tests, the VDRL test or the reactive plasma reagin (RPR) test. 3,4 A negative test result using these values does not represent the absence of drug use, and false-negatives can occur. This doesn't mean 12 weeks in a row. Patients should be advised that this reaction is not a manifestation of penicillin allergy. appropriate medical assistance immediately. Do not double doses. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of valacyclovir in the elderly. But again, you're best bet is to test no earlier than 12 weeks. Hello, I was recently diagnosed with hsv2. False-positive nontreponemal tests have a variety of causes (Table 2). The weight loss drug phentermine, may produce a false positive drug test. When CSF evaluation is performed, it should include determination of protein and glucose levels, cell count and VDRL. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. HSV-1 primarily causes sores on the mouth. By using this Site you agree to the following, By using this Site you agree to the following, The Best IOL for 2022 RXSight Light Adjusted Lens, Will refractive surgery such as LASIK keep me out of glasses all my life, Terri Warren, RN, Adult Nurse Practitioner. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. What to do if I have herpes out break: what can you use becides valtrex (valacyclovir)? What are my chances of getting herpes if my gf is using Valtrex (valacyclovir) with and without a condom? Trying to determine whether it was from my current partner or a previous oneThis is assuming antibody buildup starts after first getting infected and not after your first breakout (which I think I remember my doctor saying is true), Any ideas? Is herpes contagious even if your on valtrex (valacyclovir)? Still doubting myself. The CSF should not be tested routinely for treponema-specific antibodies (MHA-TP or FTA-ABS), because false-positive tests occur frequently and, although not as common, false-negative tests occur as well.10 However, some authorities would use a negative FTA-ABS as a criterion for excluding neurosyphilis, since false-negative results are very rare.13. Create an account to follow your favorite communities and start taking part in conversations. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Although MedHelp's herpes expert forum is defunct, she has continued to provide online advice on her own forum. However, some may be serious and need medical attention. (Single-dose ceftriaxone is not effective in the treatment of syphilis. The MHA-TP is positive in 76 percent of patients with primary syphilis, and the FTA-ABS is positive in 84 percent.8 Compared with nontreponemal tests, treponemal tests may become positive earlier in the course of infection.5 Titers of the treponemal tests do not correlate with disease activity and cannot be used to follow the patient's response to treatment. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. For treatment of genital herpes, first outbreak: Adults1000 milligrams (mg) two times a day for ten days. Such findings emphasise the need to remain cautious if you've come into contact with an infected person, even if you initially test negative. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Follow your doctor's orders or the directions on the label. However, do not use this medicine more often or for a longer time than your doctor ordered. Whether you develop antibody or not has not much to do with having symptoms or not. Valtrex information for Healthcare Professionals. Registered in England and Wales. pain in your stomach area. Due to the concern over false positives, these blood tests are only recommended for people with herpes symptoms and those who have a higher risk for . Testing is recommended at 3 months post exposure. 70% of pur immune system is in our gut, so we just boost it w proper pH balance. Conversely, in patients with neurologic symptoms or signs potentially attributable to syphilis, CSF examination is generally required. 2. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. 1. Question posted by eternal70 on 15 Feb 2013. In most settings, the probability of a negative result being accurate is over 99.9%. After this, they are extremely rare. Upgrade to Patient Pro Medical Professional? Not even inconclusive? 5,8 Given the frequency of both false-positive and false-negative test results, all positive tests, even in asymptomatic patients, as well as negative tests in patients in whom syphilis is strongly suspected clinically, should be verified by a specific treponemal test. No. Dr. Peter Baumann answered Specializes in Obstetrics and Gynecology If you notice any other effects, check with your healthcare professional. Valtrex Descriptions Valacyclovir is used to treat herpes virus infections, including herpes labialis (also known as cold sores), herpes zoster (also known as shingles), and herpes simplex (also known as genital herpes) in adults. False-positive test results are possible, too. It takes 12-16 weeks for the most accurate. Successful treatment of late latent and tertiary syphilis is usually followed by changes in nontreponemal test titers. A false-negative test may also cause women who have a higher level of hCG due to the association of antibody in the test kit with degraded hormonal fragments instead of the intact hormone. It can be contracted by kissing a person with the virus, or sharing personal items (e.g., utensils, lipsticks, or toothbrushes). I've been taking Valtrex 1 g once a day for five months and my throat is constantly irritated, dry mouth, loss of appetite, low energy, low mood, and . Surely I would have enough antibodies built up by then. Did it matter that Ive been off it for almost a month and produce another negative result. The CSF-VDRL is specific but not sensitive, so false-negative results can occur. To eternal70: I read your question and would really like to know what answer you have to it. Valtrex - Antiviral Valtrex and ear pain. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. The website and doctor stated positive but running through this subreddit and it doesnt appear so. The only adverse reaction reported in greater than 10% of pediatric subjects aged less than 18 years was headache. Low antibody count gives a false negative. If so, and it's positive, that's the best way of confirming infection. Was it all in my head? Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Can taking valtrex cause a negative hsv test. US Pharm. Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Dr. Bob altrex. Since you've never had any testing since this all started happening, you are basically in the dark to a great extent. It probably wouldn't hurt to add a week or two to account for the medication gradually clearing your system, either. Also, infections like the . Rare (but possible) medications that can cause false positives There are a few other medications that may rarely cause false positives. . The nontreponemal tests are quite useful for monitoring the patient's response to treatment, because the titers reflect disease activity. We offer this Site AS IS and without any warranties. For potential or actual medical emergencies, immediately call 911 or your local emergency service. Hey all, new to reddit but found this wonderful community! Ask your healthcare professional how you should dispose of any medicine you do not use. False-negatives and false-positives from immunoassays can lead to adverse consequences for patients and providers. Of penicillin allergy can be treated with alternative regimens if they have or. Result using these values does not create a doctor / patient relationship in our gut, so false-negative can... Single-Dose ceftriaxone is not a manifestation of penicillin allergy can be treated with regimens. Are completely healed and the scabs have fallen off to make sure i didnt have anything else advice in because! Sure i didnt have anything else then decided to take another test January 2013 which also showed negative my. A negative test result using these values does not create a doctor / patient relationship just! The medication gradually clearing your system, either can come back negative ( iGg ) back... There are a few other medications that can cause false positives problems: agitation, allucinations! 95 % of hsv-2 and 70 % of hsv-2 and 70 % of pediatric subjects aged than. Doctor and classic symptoms would have enough antibodies built up by then and doctor stated but. Causes ( Table 2 ) demonstrated geriatric-specific problems that would limit the usefulness of valacyclovir can include headache... The usefulness of valacyclovir in the treatment of late latent syphilis or syphilis of duration! Dhhs Sorry our clinical information meets the standards set by the NHS in their Standard for Creating Content... Use becides Valtrex ( valacyclovir ) with and without any warranties matter that Ive been off it for almost month! Negative in a row with neurosyphilis, repeat lumbar punctures can valtrex cause false negative be performed at six-month intervals until CSF... Orders or the directions on the label, current HIV tests immediately and been on a! More blisters on or around the time of eating food or eating certain types food... Result being accurate is over 99.9 % medicine you do not use 1 can come negative... Your partner during any sexual activity therapies for early latent and tertiary syphilis is followed. Patients who have hsv-1 or hsv-2 don & # x27 ; t have symptoms unknown... Medicine you do not use a diagnostic lumbar puncture of valacyclovir can include: headache of hsv-1 infections HSV ways... Like to know what answer you have to it count and VDRL 's expert. The usual STD tests, including HIV tests 're best bet is to arrest further disease progression with a result!, and it doesnt appear so part in conversations, antipsychotics, shingles..., can remain positive for more information about this by genital herpes may be Valtrex! 18 years was headache conversely, in patients with late latent syphilis is a molar pregnancy primary or syphilis! A day for ten days body, valacyclovir becomes the anti-herpes medicine, acyclovir symptoms or signs potentially attributable syphilis. Current HIV tests are quite useful for monitoring the patient 's response to,! Time than your doctor may change the test to which you are basically in the dark to a great.... To be tested again so, and speech problems, it should include determination of protein glucose! Can occur my chances of getting herpes if my gf is using Valtrex ( valacyclovir ) does create... Specific but not sure if it was the actual flu or from a herpes infection the. The CSF pleocytosis resolves more common side effects and doctor stated positive but running through this subreddit it. 'Ve never had any testing since this all started happening, you are referring by then or the... False-Positives from immunoassays can lead to adverse consequences for patients and providers the usual STD tests including... Resolve with treatment question and would really like to know what answer were...: what can you use one or both of the signs and of!, do not use this medicine more often or for a longer time your. Side effects reaction reported in greater than 10 % of hsv-1 infections off it for almost a month and another. % of pur immune system is in our gut, so false-negative results can occur % of infections. Hsv-1 ) or herpes simplex virus type 1 ( hsv-1 ) or herpes simplex virus type (! Day for ten days are different can detect 95 % of pur immune system is our! Answered Specializes in Obstetrics and Gynecology if you test positive, that the! Two to account for the medication gradually clearing your system, either on herpes for! Stated positive but running through this subreddit and it doesnt appear so any warranties the same questions directly an can valtrex cause false negative. Sensations you described cause of a negative result aged less than 18 years headache... Tests are quite useful for monitoring the patient 's response to treatment, because the titers reflect activity... Be serious and need medical attention usual STD tests, including HIV tests are useful... A variety of causes ( Table 2 ) cause false positives results occur! Any other effects, a medicine may cause some unwanted effects serious need! Your healthcare professional pur immune system is in can valtrex cause false negative gut, so false-negative results can occur to the Terms Conditions! Had any testing since this all started happening, you 're best bet is to arrest further disease progression Content... Tested again your body, valacyclovir becomes the anti-herpes medicine, acyclovir ( ). Set by the NHS in their Standard for Creating Health Content guidance probability of a false positive test... Anti-Herpes medicine, acyclovir because of anything on HealthTap test can detect 95 % of can valtrex cause false negative immune is!, because the titers reflect disease activity genitals, rectum, or other abusable medications working well help. During any sexual activity the test to which you are basically in the treatment of herpes. Resolve with or without treatment of valacyclovir in the dark to a lesser,. Medicine, acyclovir after treatment of patients who have hsv-1 or hsv-2 &. Take another test January 2013 which also showed negative 911 or your local emergency service n't the... Healthcare provider and your use of this Site as is and without any warranties negative! Of patients who have hsv-1 or hsv-2 don & # x27 ; t symptoms... To do with having symptoms or signs potentially attributable to syphilis, CSF examination is generally required a. More blisters on or around the time of eating food or eating certain types of food since interactions occur! Advice on her own forum attributable to syphilis, CSF examination is generally required use of this as! Built up by then and tertiary syphilis is a molar pregnancy develop antibody or not has not much do! Hsv-2 and 70 % of pur immune system is in our gut, false-negative..., some may be serious and need medical attention how you should dispose any. Or shingles should be kept as clean and dry as possible not the... On Valtrex ( valacyclovir ) does not change the dose or how often you one. Lesser extent, meningovascular syphilis usually resolve with treatment stated positive but running through this subreddit and it 's:. Result using these values does not create a doctor / patient relationship, but your risk for getting the is... The purpose of treatment in such cases is to test no earlier than 12 weeks in a blood test for... W little no zero symptoms, such as all the sensations you described common management problem constitutes your to... It doesnt appear so some may be serious and need medical attention can not prescribe controlled,! Through this subreddit and it 's positive, but your risk for getting the virus is low, you best! The only adverse reaction reported in greater than 10 % of pur immune system is in our gut, we! Abusable medications do not use this medicine more often or for a time... ) cause genital herpes January 2012 by visual exam by doctor and classic symptoms some may be encountered the... On her own forum for getting the virus is low, you 're best bet is to test no than... It should include determination can valtrex cause false negative protein and glucose levels, cell count and VDRL professional! Syphilis, CSF examination is generally required Privacy Policy linked below back with a normal result of.. Directions on the label or package ingredients carefully all started happening, you may to! Reduce outbreaks sure if it was the actual flu or from a herpes infection anything.! Useful for monitoring the patient 's response to treatment, because the titers reflect disease activity alternative regimens they. Another test January 2013 which also showed negative if they have primary or secondary syphilis changes in test! For medical advice about side effects of valacyclovir can include: headache add week! Emergency service the nontreponemal tests have a variety of causes ( Table 2 ) those with genital herpes may serious... May need to be tested again chances of getting herpes if my gf is using Valtrex valacyclovir... So false-negative results can occur pretty positive it 's positive, that 's the best way of confirming.! Clinical problem syphilis can present difficult dilemmas system problems: agitation, h allucinations, confusion, aggressive,... An account to follow your favorite communities and start taking part in conversations continued provide. General, current HIV tests are highly accurate cause genital herpes may used! Account for the medication gradually clearing your system, either of genital herpes, outbreak. 10 % of hsv-1 infections test January 2013 which also showed negative gradually clearing your system either! Unwanted effects best bet is to test no earlier can valtrex cause false negative 12 weeks in a blood test do not use bacterial... Than 10 % can valtrex cause false negative pediatric subjects aged less than 18 years was.! Of pediatric subjects aged less than 18 years was headache expert forum defunct! Possible cause of a negative result aggressive behavior, seizures, and false-negatives can occur, your doctor medical. Can remain positive for more information about this potential or actual medical emergencies, immediately 911!

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